Gladys de Leon Boenig
Publications by Year
Research Areas
Protein Degradation and Inhibitors, Multiple Myeloma Research and Treatments, Monoclonal and Polyclonal Antibodies Research, Magnetism in coordination complexes, Retinoids in leukemia and cellular processes
Most-Cited Works
- → Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung(2015)238 cited
- → GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP)(2017)126 cited
- → Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637)(2016)111 cited
- → Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300(2016)94 cited
- → Minor Structural Change to Tertiary Sulfonamide RORc Ligands Led to Opposite Mechanisms of Action(2014)82 cited
- → Design of a brain-penetrant CDK4/6 inhibitor for glioblastoma(2019)64 cited
- → Structure-based design of substituted hexafluoroisopropanol-arylsulfonamides as modulators of RORc(2013)62 cited
- → Reduction in lipophilicity improved the solubility, plasma–protein binding, and permeability of tertiary sulfonamide RORc inverse agonists(2014)49 cited
- → Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members(2019)48 cited
- → A reversed sulfonamide series of selective RORc inverse agonists(2014)35 cited