Patrick Leroy
Publications by Year
Research Areas
Microtubule and mitosis dynamics, Ubiquitin and proteasome pathways, Cell death mechanisms and regulation, Autophagy in Disease and Therapy, Health, Medicine and Society
Most-Cited Works
- → Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase(2007)413 cited
- → Characterization of Alisertib (MLN8237), an Investigational Small-Molecule Inhibitor of Aurora A Kinase Using Novel In Vivo Pharmacodynamic Assays(2011)300 cited
- → Plasmodium falciparum erythrocyte membrane protein 1 is anchored to the actin–spectrin junction and knob-associated histidine-rich protein in the erythrocyte skeleton(2000)145 cited
- → Localization of Human TACC3 to Mitotic Spindles Is Mediated by Phosphorylation on Ser558 by Aurora A: A Novel Pharmacodynamic Method for Measuring Aurora A Activity(2007)128 cited
- → MLN8054 and Alisertib (MLN8237): Discovery of Selective Oral Aurora A Inhibitors(2015)108 cited
- → Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib(2010)103 cited
- → Identification of a lung cancer cell line deficient in atg7-dependent autophagy(2015)52 cited
- → The cytoadherence ligand Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) binds to the P. falciparum Knob-associated Histidine-rich Protein (KAHRP) by electrostatic interactions(2000)32 cited
- → Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors(2020)30 cited
- MLN8237: an orally active small molecule inhibitor of Aurora A kinase in phase I clinical trials(2008)