Takahisa Hanada
Eisai (Japan)(JP)
Publications by Year
Research Areas
Neuroscience and Neuropharmacology Research, Epilepsy research and treatment, Pharmacological Effects and Toxicity Studies, Ion channel regulation and function, HER2/EGFR in Cancer Research
Most-Cited Works
- → Perampanel: A novel, orally active, noncompetitive AMPA-receptor antagonist that reduces seizure activity in rodent models of epilepsy(2011)400 cited
- → Preclinical pharmacology of perampanel, a selective non-competitive AMPA receptor antagonist(2013)235 cited
- → Ionotropic Glutamate Receptors in Epilepsy: A Review Focusing on AMPA and NMDA Receptors(2020)231 cited
- → Discovery of 2-(2-Oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl)benzonitrile (Perampanel): A Novel, Noncompetitive α-Amino-3-hydroxy-5-methyl-4-isoxazolepropanoic Acid (AMPA) Receptor Antagonist(2012)177 cited
- → The discovery and development of perampanel for the treatment of epilepsy(2014)86 cited
- → Ultra-high-dose methylcobalamin in amyotrophic lateral sclerosis: a long-term phase II/III randomised controlled study(2019)77 cited
- → Involvement of P-type calcium channels in high potassium-elicited release of neurotransmitters from rat brain slices(1995)58 cited
- → Effect of perampanel, a novel AMPA antagonist, on benzodiazepine‐resistant status epilepticus in a lithium‐pilocarpine rat model(2014)58 cited
- → Pharmacodynamic and pharmacokinetic interactions of perampanel and other antiepileptic drugs in a rat amygdala kindling model(2014)32 cited
- → The AMPA receptor as a therapeutic target in epilepsy: preclinical and clinical evidence(2014)32 cited