Guillaume Lessène
The University of Melbourne(AU)Walter and Eliza Hall Institute of Medical Research(AU)
Publications by Year
Research Areas
Cell death mechanisms and regulation, Protein Degradation and Inhibitors, Histone Deacetylase Inhibitors Research, Computational Drug Discovery Methods, Ubiquitin and proteasome pathways
Most-Cited Works
- → Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy(2013)3,145 cited
- → The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models(2016)1,037 cited
- → BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis(2018)972 cited
- → Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production(2014)924 cited
- → BCL-2 family antagonists for cancer therapy(2008)613 cited
- → Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death(2014)588 cited
- → Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2