Robert W. Carling
C4X Discovery (United Kingdom)(GB)
Publications by Year
Research Areas
Neuroscience and Neuropharmacology Research, Pharmacological Receptor Mechanisms and Effects, Synthetic Organic Chemistry Methods, Synthesis and Biological Evaluation, Phenothiazines and Benzothiazines Synthesis and Activities
Most-Cited Works
- → Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABAA receptor α1 subtype(2000)938 cited
- → TPA023 [7-(1,1-Dimethylethyl)-6-(2-ethyl-2 H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine], an Agonist Selective for α2- and α3-Containing GABAA Receptors, Is a Nonsedating Anxiolytic in Rodents and Primates(2005)189 cited
- → 4-Amido-2-carboxytetrahydroquinolines. Structure-activity relationships for antagonism at the glycine site of the NMDA receptor(1992)187 cited
- → Kynurenic acid derivatives. Structure-activity relationships for excitatory amino acid antagonism and identification of potent and selective antagonists at the glycine site on the N-methyl-D-aspartate receptor(1991)144 cited
- → 3-Phenyl-6-(2-pyridyl)methyloxy-1,2,4-triazolo[3,4-a]phthalazines and Analogues: High-Affinity γ-Aminobutyric Acid-A Benzodiazepine Receptor Ligands with α2, α3, and α5-Subtype Binding Selectivity over α1(2004)135 cited
- → Effect of Plasma Protein Binding on in Vivo Activity and Brain Penetration of Glycine/NMDA Receptor Antagonists