Thomas Hunsaker
Publications by Year
Research Areas
Cancer, Hypoxia, and Metabolism, Glutathione Transferases and Polymorphisms, Melanoma and MAPK Pathways, Lung Cancer Treatments and Mutations, Estrogen and related hormone effects
Most-Cited Works
- → Crossinhibitory Activities of Ngn1 and Math1 Allow Specification of Distinct Dorsal Interneurons(2001)304 cited
- → An Integrated Genomic Screen Identifies LDHB as an Essential Gene for Triple-Negative Breast Cancer(2012)197 cited
- → Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development(2016)157 cited
- → ARAF mutations confer resistance to the RAF inhibitor belvarafenib in melanoma(2021)133 cited
- → GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP)(2017)126 cited
- → Distinct domains within Mash1 and Math1 are required for function in neuronal differentiation versus neuronal cell-type specification(2004)110 cited
- → Entrectinib, a TRK/ROS1 inhibitor with anti-CNS tumor activity: differentiation from other inhibitors in its class due to weak interaction with P-glycoprotein(2020)101 cited
- → Zic1 represses Math1 expression via interactions with the Math1 enhancer and modulation of Math1 autoregulation(2003)96 cited
- → Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300(2016)94 cited
- → Pan-Cancer Metabolic Signature Predicts Co-Dependency on Glutaminase and De Novo Glutathione Synthesis Linked to a High-Mesenchymal Cell State(2018)92 cited