Emmanouil Metzakopian
Babraham Institute(GB)UK Dementia Research Institute(GB)
Publications by Year
Research Areas
CRISPR and Genetic Engineering, Autophagy in Disease and Therapy, Nuclear Receptors and Signaling, Single-cell and spatial transcriptomics, Genetics and Neurodevelopmental Disorders
Most-Cited Works
- → A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia(2016)815 cited
- → Predicting the mutations generated by repair of Cas9-induced double-strand breaks(2018)522 cited
- → ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks(2019)180 cited
- → UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs(2018)166 cited
- → Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development(2009)156 cited
- → Single-Cell Transcriptomics of Parkinson’s Disease Human In Vitro Models Reveals Dopamine Neuron-Specific Stress Responses(2020)140 cited
- → ER-mitochondria contact sites in neurodegeneration: genetic screening approaches to investigate novel disease mechanisms(2020)135 cited
- → Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing(2019)129 cited
- → Unravelling cell type-specific responses to Parkinson’s Disease at single cell resolution(2024)96 cited
- → SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4(2018)88 cited