Constantine Kreatsoulas
Sunesis (United States)(US)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Cancer-related Molecular Pathways, DNA Repair Mechanisms, Machine Learning in Materials Science, Advanced Breast Cancer Therapies
Most-Cited Works
- → Comparison of Topological, Shape, and Docking Methods in Virtual Screening(2007)415 cited
- → Selective activation of the M 1 muscarinic acetylcholine receptor achieved by allosteric potentiation(2009)284 cited
- → Current and Future Roles of Artificial Intelligence in Medicinal Chemistry Synthesis(2020)238 cited
- → Development of thioquinazolinones, allosteric Chk1 kinase inhibitors(2008)74 cited
- → 3-(Indol-2-yl)indazoles as Chek1 kinase inhibitors: Optimization of potency and selectivity via substitution at C6(2006)46 cited
- → Optimization of a pyrazoloquinolinone class of Chk1 kinase inhibitors(2007)44 cited
- → Development of 6-substituted indolylquinolinones as potent Chek1 kinase inhibitors(2006)37 cited
- → Discovery of Pyrazolocarboxamides as Potent and Selective Receptor Interacting Protein 2 (RIP2) Kinase Inhibitors(2019)26 cited
- → The M1 Muscarinic Receptor Allosteric Agonists AC-42 and 1-[1′-(2-Methylbenzyl)-1,4′-bipiperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one Bind to a Unique Site Distinct from the Acetylcholine Orthosteric Site(2010)25 cited
- → Synthesis and evaluation of substituted benzoisoquinolinones as potent inhibitors of Chk1 kinase(2007)25 cited