Brian E. Looker

Publications by Year

Research Areas

Asthma and respiratory diseases, Allergic Rhinitis and Sensitization, Receptor Mechanisms and Signaling, Neuropeptides and Animal Physiology, Synthesis and Catalytic Reactions

Most-Cited Works

• → Synthesis and Structure−Activity Relationships of Long-acting β₂Adrenergic Receptor Agonists Incorporating Metabolic Inactivation: An Antedrug Approach(2010)98 cited
• → Synthesis and Structure−Activity Relationships of Long-acting β₂Adrenergic Receptor Agonists Incorporating Arylsulfonamide Groups(2009)45 cited
• → The Discovery of Phthalazinone-Based Human H₁and H₃Single-Ligand Antagonists Suitable for Intranasal Administration for the Treatment of Allergic Rhinitis(2011)30 cited
• → 4-Acyl-1-(4-aminoalkoxyphenyl)-2-ketopiperazines as a Novel Class of Non-Brain-Penetrant Histamine H₃ Receptor Antagonists(2007)24 cited
• → Discovery of a Rapidly Metabolized, Long-Acting β₂Adrenergic Receptor Agonist with a Short Onset Time Incorporating a Sulfone Group Suitable for Once-Daily Dosing(2013)23 cited
• → Water-soluble steroidal anaesthetics(1979)21 cited
• → 4-Alkyl-thio- and -dithio-azetidinones from penicillins(1971)21 cited
• → Transformations of penicillins. Part V. Reactions of olefin and acetylene derivatives with the sulphenic acid intermediates from penicillin S-oxides(1973)17 cited
• → The discovery of long-acting saligenin β2 adrenergic receptor agonists incorporating hydantoin or uracil rings(2011)16 cited
• → Design of Phthalazinone Amide Histamine H₁ Receptor Antagonists for Use in Rhinitis(2017)13 cited