R. van de Straat
Publications by Year
Research Areas
Drug Transport and Resistance Mechanisms, Drug-Induced Hepatotoxicity and Protection, Pharmacogenetics and Drug Metabolism, Diverse Scientific and Economic Studies, BIM and Construction Integration
Most-Cited Works
- → Abstract of papers(1987)428 cited
- → Molecular Aspects of Paracetamol-Induced Hepatotoxicity and its Mechanism-Based Prevention(1992)318 cited
- → The mechanism of prevention of paracetamol-induced hepatotoxicity by 3,5-dialkyl substitution(1987)78 cited
- → Cytochrome P-450-mediated oxidation of substrates by electron-transfer; Role of oxygen radicals and of 1- and 2-electron oxidation of paracetamol(1988)40 cited
- → A theoretical study on the metabolic activation of paracetamol by cytochrome P-450: indications for a uniform oxidation mechanism(1989)40 cited
- → Paracetamol, 3-monoalkyl- and 3,5-dialkyl derivatives(1986)39 cited
- → Role of hepatic microsomal and purified cytochrome P-450 in one-electron reduction of two quinone imines and concomitant reduction of molecular oxygen(1987)36 cited
- → Relationship between paracetamol binding to and its oxidation by two cytochromes P-450 isozymes—a proton nuclear magnetic resonance and spectrophotometric study(1987)29 cited
- → One-electron reduction of mitomycin c by rat liver: Role of cytochrome P-450 and NADPH-cytochrome P-450 reductase(1990)22 cited
- → Paracetamol, 3-monoalkyl- and 3,5-dialkyl-substituted derivatives(1988)20 cited