Laura O’Regan
University of Bristol(GB)
Publications by Year
Research Areas
Microtubule and mitosis dynamics, Occupational and environmental lung diseases, Genetics, Aging, and Longevity in Model Organisms, Cancer-related Molecular Pathways, Cellular transport and secretion
Most-Cited Works
- → Cell cycle regulation by the NEK family of protein kinases(2012)399 cited
- → Mitotic regulation by NIMA-related kinases(2007)218 cited
- → The Nek6 and Nek7 Protein Kinases Are Required for Robust Mitotic Spindle Formation and Cytokinesis(2009)191 cited
- → Histone deacetylase (HDAC) 1 and 2 are essential for accurate cell division and the pluripotency of embryonic stem cells(2014)166 cited
- → Crystal structure of EML1 reveals the basis for Hsp90 dependence of oncogenic EML4-ALK by disruption of an atypical β-propeller domain(2014)112 cited
- → Microtubule association of EML proteins and the EML4-ALK variant 3 oncoprotein require an N-terminal trimerization domain(2015)106 cited
- → An Autoinhibitory Tyrosine Motif in the Cell-Cycle-Regulated Nek7 Kinase Is Released through Binding of Nek9(2009)103 cited
- → Mechanistic basis of Nek7 activation through Nek9 binding and induced dimerization(2015)62 cited
- → Hsp72 is targeted to the mitotic spindle by Nek6 to promote K-fiber assembly and mitotic progression(2015)53 cited
- → Mitotic phosphorylation by NEK6 and NEK7 reduces the microtubule affinity of EML4 to promote chromosome congression(2019)51 cited