Gerald B. Grindey
Roswell Park Comprehensive Cancer Center(US)
Publications by Year
Research Areas
Biochemical and Molecular Research, Cancer therapeutics and mechanisms, HIV/AIDS drug development and treatment, Pharmacogenetics and Drug Metabolism, Folate and B Vitamins Research
Most-Cited Works
- Action of 2',2'-difluorodeoxycytidine on DNA synthesis.(1991)
- Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase.(1994)
- → Photoradiation Therapy. II. Cure of Animal Tumors With Hematoporphyrin and Light23(1975)684 cited
- Evaluation of the antitumor activity of gemcitabine (2',2'-difluoro-2'-deoxycytidine).(1990)
- Comparison of the cellular pharmacokinetics and toxicity of 2',2'-difluorodeoxycytidine and 1-beta-D-arabinofuranosylcytosine.(1988)
- → Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2',2'-difluorodeoxycytidine.(1990)406 cited
- Cellular elimination of 2',2'-difluorodeoxycytidine 5'-triphosphate: a mechanism of self-potentiation.(1992)
- → A dideazatetrahydrofolate analog lacking a chiral center at C-6: N-[4-[2-(2-amino-3,4-dihydro-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5yl)ethyl[benzoyl]-L-glutamic acid is an inhibitor of thymidylate synthase(1992)252 cited
- In vitro and in vivo antitumor activity of the phosphatidylinositol-3-kinase inhibitor, wortmannin.(1995)