Joshua P. Taygerly
Ideaya Biosciences (United States)(US)
Publications by Year
Research Areas
Renal and related cancers, CRISPR and Genetic Engineering, Animal Genetics and Reproduction, DNA Repair Mechanisms, Cell death mechanisms and regulation
Most-Cited Works
- → AMG 176, a Selective MCL1 Inhibitor, Is Effective in Hematologic Cancer Models Alone and in Combination with Established Therapies(2018)409 cited
- → Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction(2019)203 cited
- → Structure-Based Drug Design of RN486, a Potent and Selective Bruton’s Tyrosine Kinase (BTK) Inhibitor, for the Treatment of Rheumatoid Arthritis(2014)107 cited
- → A convenient guide to help select replacement solvents for dichloromethane in chromatography(2012)88 cited
- → Novel WRN Helicase Inhibitors Selectively Target Microsatellite-Unstable Cancer Cells(2024)45 cited
- → Discovery of INT131: A selective PPARγ modulator that enhances insulin sensitivity(2012)42 cited
- → Discovery of a Novel Series of Potent Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B(2013)37 cited
- → Finding the perfect spot for fluorine: Improving potency up to 40-fold during a rational fluorine scan of a Bruton’s Tyrosine Kinase (BTK) inhibitor scaffold(2014)33 cited
- → Discovery of N-[4-[6-tert-Butyl-5-methoxy-8-(6-methoxy-2-oxo-1H-pyridin-3-yl)-3-quinolyl]phenyl]methanesulfonamide (RG7109), a Potent Inhibitor of the Hepatitis C Virus NS5B Polymerase(2013)31 cited
- → Small-Molecule Antagonists of Bcl-2 Family Proteins(2012)12 cited