Brian T. Hopkins
Biogen (United States)(US)
Publications by Year
Research Areas
Chronic Lymphocytic Leukemia Research, Chemical Synthesis and Analysis, Synthetic Organic Chemistry Methods, Chronic Myeloid Leukemia Treatments, Immunodeficiency and Autoimmune Disorders
Most-Cited Works
- → Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinases(2010)149 cited
- → ROMPgel Reagents in Parallel Synthesis(2002)125 cited
- → BTK inhibition limits B-cell–T-cell interaction through modulation of B-cell metabolism: implications for multiple sclerosis therapy(2022)65 cited
- → ROMPgel-Supported Triphenylphosphine with Potential Application in Parallel Synthesis(2002)63 cited
- → Parallel Synthesis of Terminal Alkynes Using a ROMPgel-Supported Ethyl 1-Diazo-2-oxopropylphosphonate(2004)46 cited
- → ROMPgel-supported biphenyl and naphthalene: reagents for lithiation reactions with minimal purification(2002)43 cited
- → CDK12-mediated transcriptional regulation of noncanonical NF-κB components is essential for signaling(2018)38 cited
- → Discovery and Preclinical Characterization of BIIB091, a Reversible, Selective BTK Inhibitor for the Treatment of Multiple Sclerosis(2021)38 cited
- → Discovery of BIIB068: A Selective, Potent, Reversible Bruton’s Tyrosine Kinase Inhibitor as an Orally Efficacious Agent for Autoimmune Diseases(2020)37 cited
- → Facile and purification free synthesis of Mosher amides utilizing a ROMPgel supported reagent(2001)30 cited