Brian S. Sproat
Publications by Year
Research Areas
RNA and protein synthesis mechanisms, DNA and Nucleic Acid Chemistry, Advanced biosensing and bioanalysis techniques, RNA modifications and cancer, RNA Research and Splicing
Most-Cited Works
- → Lung Delivery Studies Using siRNA Conjugated to TAT(48−60) and Penetratin Reveal Peptide Induced Reduction in Gene Expression and Induction of Innate Immunity(2007)346 cited
- → Automated DNA sequencing: ultrasensitive detection of fluorescent bands during electrophoresis(1987)326 cited
- → Highly efficient chemical synthesis of 2′-O-methyloligoribonucleotides and tetrabiotinylated derivatives; novel probes that are resistant to degradation by RNA or DNA specific nucleases(1989)274 cited
- → A non-radioactive automated method for DNA sequence determination(1986)246 cited
- → Structural and Mechanistic Basis of Pre- and Posttransfer Editing by Leucyl-tRNA Synthetase(2003)223 cited
- → Nonviral siRNA Delivery to the Lung: Investigation of PEG−PEI Polyplexes and Their In Vivo Performance(2009)187 cited
- → Antisense probing of the human U4U6 snRNP with biotinylated 2′-OMe RNA oligonucleotides(1989)169 cited
- → In vivo detection of snRNP-rich organelles in the nuclei of mammalian cells.(1991)168 cited
- → Crystal Structures at 2.5 Angstrom Resolution of Seryl-tRNA Synthetase Complexed with Two Analogs of Seryl Adenylate(1994)163 cited
- → Nuclease resistant ribozymes with high catalytic activity.(1992)147 cited