Patrick Cullen
Translational Genomics Research Institute(US)
Publications by Year
Research Areas
Single-cell and spatial transcriptomics, Chronic Lymphocytic Leukemia Research, Neurogenetic and Muscular Disorders Research, Cell Image Analysis Techniques, Neuroinflammation and Neurodegeneration Mechanisms
Most-Cited Works
- → Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinases(2010)149 cited
- → SMN deficiency in severe models of spinal muscular atrophy causes widespread intron retention and DNA damage(2017)126 cited
- → Cx3cr1-deficient microglia exhibit a premature aging transcriptome(2019)103 cited
- → Association between changes in gene signatures expression and disease activity among patients with systemic lupus erythematosus(2019)83 cited
- → Organotypic Brain Slice Culture Microglia Exhibit Molecular Similarity to Acutely-Isolated Adult Microglia and Provide a Platform to Study Neuroinflammation(2020)69 cited
- → MOG autoantibodies trigger a tightly-controlled FcR and BTK-driven microglia proliferative response(2021)61 cited
- → Pharmacodynamics of Dimethyl Fumarate Are Tissue Specific and Involve NRF2-Dependent and -Independent Mechanisms(2016)57 cited
- → Small molecule mediated inhibition of RORγ‐dependent gene expression and autoimmune disease pathology in vivo(2015)51 cited
- → Identification of regulators of the myofibroblast phenotype of primary dermal fibroblasts from early diffuse systemic sclerosis patients(2019)50 cited
- → Dimethyl fumarate alters microglia phenotype and protects neurons against proinflammatory toxic microenvironments(2016)50 cited