Luc Pilotte
Ludwig Cancer Research(BE)de Duve Institute(BE)
Publications by Year
Research Areas
Tryptophan and brain disorders, Inflammatory mediators and NSAID effects, Immune cells in cancer, Stress Responses and Cortisol, Cancer Immunotherapy and Biomarkers
Most-Cited Works
- → Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase(2003)2,279 cited
- → Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase(2012)566 cited
- → Extensive Profiling of the Expression of the Indoleamine 2,3-Dioxygenase 1 Protein in Normal and Tumoral Human Tissues(2014)361 cited
- → Tryptophan 2,3-Dioxygenase (TDO) Inhibitors. 3-(2-(Pyridyl)ethenyl)indoles as Potential Anticancer Immunomodulators(2011)180 cited
- → Constitutive IDO1 Expression in Human Tumors Is Driven by Cyclooxygenase-2 and Mediates Intrinsic Immune Resistance(2017)173 cited
- → Rational Design of 4-Aryl-1,2,3-Triazoles for Indoleamine 2,3-Dioxygenase 1 Inhibition(2012)168 cited
- → Tryptophan depletion sensitizes the AHR pathway by increasing AHR expression and GCN2/LAT1-mediated kynurenine uptake, and potentiates induction of regulatory T lymphocytes(2023)93 cited
- → Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1in juvenile diabetes(2018)72 cited
- → Detailed analysis and follow-up studies of a high-throughput screening for indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors(2014)69 cited
- → Inhibition of Tryptophan-Dioxygenase Activity Increases the Antitumor Efficacy of Immune Checkpoint Inhibitors(2019)68 cited