Sébastien Laliberté
OmegaChem (Canada)(CA)AstraZeneca (Canada)(CA)
Publications by Year
Research Areas
Receptor Mechanisms and Signaling, Renin-Angiotensin System Studies, Catalytic C–H Functionalization Methods, Neurobiology and Insect Physiology Research, Crystallography and molecular interactions
Most-Cited Works
- → The Discovery of Setileuton, a Potent and Selective 5-Lipoxygenase Inhibitor(2010)79 cited
- → Discovery of MK-0952, a selective PDE4 inhibitor for the treatment of long-term memory loss and mild cognitive impairment(2010)43 cited
- → Oxidation of aromatic and aliphatic triisopropylsilanylsulfanyls to sulfonyl chlorides: preparation of sulfonamides(2003)31 cited
- → Optimization and structure–activity relationship of a series of 1-phenyl-1,8-naphthyridin-4-one-3-carboxamides: Identification of MK-0873, a potent and effective PDE4 inhibitor(2008)20 cited
- → Palladium-catalyzed double allylic alkylation of indole-2-hydroxamates: easy access to pyrazino[1,2-a]indole derivatives(2009)19 cited
- → Design and optimization of a substituted amino propanamide series of renin inhibitors for the treatment of hypertension(2010)17 cited
- → Renin inhibitors for the treatment of hypertension: Design and optimization of a novel series of pyridone-substituted piperidines(2011)17 cited
- → Addressing time-dependent CYP 3A4 inhibition observed in a novel series of substituted amino propanamide renin inhibitors, a case study(2010)16 cited
- → Discovery of a 4-aryloxy-1H-pyrrolo[3,2-c]pyridine and a 1-aryloxyisoquinoline series of TRPA1 antagonists(2014)15 cited
- → Renin inhibitors for the treatment of hypertension: Design and optimization of a novel series of spirocyclic piperidines(2011)15 cited