Michelle Tran‐Dubé
Pfizer (United States)(US)Université Bourgogne Franche-Comté(FR)
Publications by Year
Research Areas
Catalytic C–H Functionalization Methods, Cancer-related gene regulation, Catalytic Cross-Coupling Reactions, Cyclopropane Reaction Mechanisms, Crystallization and Solubility Studies
Most-Cited Works
- → Structure Based Drug Design of Crizotinib (PF-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal–Epithelial Transition Factor (c-MET) Kinase and Anaplastic Lymphoma Kinase (ALK)(2011)909 cited
- → A peptide-catalyzed asymmetric Stetter reaction(2004)134 cited
- → Discovery of a Novel Class of Exquisitely Selective Mesenchymal-Epithelial Transition Factor (c-MET) Protein Kinase Inhibitors and Identification of the Clinical Candidate 2-(4-(1-(Quinolin-6-ylmethyl)-1 H -[1,2,3]triazolo[4,5- b ]pyrazin-6-yl)-1 H -pyrazol-1-yl)ethanol (PF-04217903) for the Treatment of Cancer(2012)103 cited
- → Anti-selective [3+2] (Hetero)annulation of non-conjugated alkenes via directed nucleopalladation(2020)62 cited
- → Synthesis of Small 3-Fluoro- and 3,3-Difluoropyrrolidines Using Azomethine Ylide Chemistry(2015)54 cited
- → Lessons from (S)-6-(1-(6-(1-Methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)ethyl)quinoline (PF-04254644), an Inhibitor of Receptor Tyrosine Kinase c-Met with High Protein Kinase Selectivity but Broad Phosphodiesterase Family Inhibition Leading to Myocardial Degeneration in Rats(2013)39 cited
- → Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain(2018)38 cited
- → Synthesis of Aryl Ethers via a Sulfonyl Transfer Reaction(2012)37 cited
- → Copper-Catalyzed Chan–Lam Cyclopropylation of Phenols and Azaheterocycles(2018)34 cited
- → Mapping Ambiphile Reactivity Trends in the Anti‐(Hetero)annulation of Non‐Conjugated Alkenes via PdII/PdIV Catalysis(2022)33 cited