L. Govindasamy
Publications by Year
Research Areas
Virus-based gene therapy research, Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Enzyme function and inhibition, Synthesis and biological activity
Most-Cited Works
- → Next generation of adeno-associated virus 2 vectors: Point mutations in tyrosines lead to high-efficiency transduction at lower doses(2008)545 cited
- → Phase 1 Gene Therapy for Duchenne Muscular Dystrophy Using a Translational Optimized AAV Vector(2011)390 cited
- → Novel Properties of Tyrosine-mutant AAV2 Vectors in the Mouse Retina(2010)263 cited
- → Single Amino Acid Changes Can Influence Titer, Heparin Binding, and Tissue Tropism in Different Adeno-Associated Virus Serotypes(2006)231 cited
- → Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression(2008)223 cited
- → Engineering Liver-detargeted AAV9 Vectors for Cardiac and Musculoskeletal Gene Transfer(2011)218 cited
- → Structurally Mapping the Diverse Phenotype of Adeno-Associated Virus Serotype 4(2006)199 cited
- → Adeno-Associated Virus Type 2 Contains an Integrin α5β1 Binding Domain Essential for Viral Cell Entry(2006)180 cited
- → Atomic Crystal and Molecular Dynamics Simulation Structures of Human Carbonic Anhydrase II: Insights into the Proton Transfer Mechanism,(2007)164 cited
- → Structural and Kinetic Characterization of Active-Site Histidine as a Proton Shuttle in Catalysis by Human Carbonic Anhydrase II,(2005)160 cited