Jiasheng Fu
Publications by Year
Research Areas
Cancer-related Molecular Pathways, Microtubule and mitosis dynamics, Advanced Breast Cancer Therapies, Ubiquitin and proteasome pathways, Receptor Mechanisms and Signaling
Most-Cited Works
- → Discovery of AMG 232, a Potent, Selective, and Orally Bioavailable MDM2–p53 Inhibitor in Clinical Development(2014)291 cited
- → Selective and Potent Morpholinone Inhibitors of the MDM2–p53 Protein–Protein Interaction(2014)83 cited
- → Discovery of AMG 925, a FLT3 and CDK4 Dual Kinase Inhibitor with Preferential Affinity for the Activated State of FLT3(2014)70 cited
- → Novel Inhibitors of the MDM2-p53 Interaction Featuring Hydrogen Bond Acceptors as Carboxylic Acid Isosteres(2014)54 cited
- → Discovery of AM-7209, a Potent and Selective 4-Amidobenzoic Acid Inhibitor of the MDM2–p53 Interaction(2014)47 cited
- → Identification and optimization of N3,N6-diaryl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamines as a novel class of ACK1 inhibitors(2008)36 cited
- → Discovery of Potent and Simplified Piperidinone-Based Inhibitors of the MDM2–p53 Interaction(2014)27 cited
- → Discovery and optimization of a novel Neuromedin B receptor antagonist(2009)25 cited
- → Discovery of a new class of ghrelin receptor antagonists(2012)23 cited
- → Design and Synthesis of Protein Superfamily-Targeted Chemical Libraries for Lead Identification and Optimization(2005)22 cited