Tomohiro Kawamoto
Publications by Year
Research Areas
Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Microtubule and mitosis dynamics, Melanoma and MAPK Pathways, Synthesis and biological activity
Most-Cited Works
- → TAK-242 selectively suppresses Toll-like receptor 4-signaling mediated by the intracellular domain(2008)315 cited
- → Aneuploidy generates proteotoxic stress and DNA damage concurrently with p53-mediated post-mitotic apoptosis in SAC-impaired cells(2015)198 cited
- → CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor(2017)136 cited
- → 2-{3-[4-(Alkylsulfinyl)phenyl]-1-benzofuran-5-yl}-5-methyl-1,3,4-oxadiazole Derivatives as Novel Inhibitors of Glycogen Synthase Kinase-3β with Good Brain Permeability(2009)123 cited
- → Discovery of a Selective Kinase Inhibitor (TAK-632) Targeting Pan-RAF Inhibition: Design, Synthesis, and Biological Evaluation of C-7-Substituted 1,3-Benzothiazole Derivatives(2013)112 cited
- → Discovery of Potent Mcl-1/Bcl-xL Dual Inhibitors by Using a Hybridization Strategy Based on Structural Analysis of Target Proteins(2013)108 cited
- → Design, synthesis and structure–activity relationships of 1,3,4-oxadiazole derivatives as novel inhibitors of glycogen synthase kinase-3β(2009)106 cited
- → Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (2)(2008)90 cited
- → TAK-960, a Novel, Orally Available, Selective Inhibitor of Polo-Like Kinase 1, Shows Broad-spectrum Preclinical Antitumor Activity in Multiple Dosing Regimens(2011)77 cited
- → Design and Synthesis of Novel DFG-Out RAF/Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Inhibitors. 1. Exploration of [5,6]-Fused Bicyclic Scaffolds(2012)77 cited