Simona Cotesta
Novartis (Switzerland)(CH)Novartis (China)(CN)Novartis Foundation(CH)
Publications by Year
Research Areas
Protein Structure and Dynamics, Synthesis and biological activity, Bioactive Compounds and Antitumor Agents, Biochemical and Molecular Research, Bone health and treatments
Most-Cited Works
- → Discovery of Asciminib (ABL001), an Allosteric Inhibitor of the Tyrosine Kinase Activity of BCR-ABL1(2018)436 cited
- → Selective and Specific Inhibition of the Plasmodium falciparum Lysyl-tRNA Synthetase by the Fungal Secondary Metabolite Cladosporin(2012)236 cited
- → Discovery, Preclinical Characterization, and Early Clinical Activity of JDQ443, a Structurally Novel, Potent, and Selective Covalent Oral Inhibitor of KRASG12C(2022)132 cited
- → Binding or Bending: Distinction of Allosteric Abl Kinase Agonists from Antagonists by an NMR-Based Conformational Assay(2010)125 cited
- → Assessment of Docking Poses: Interactions-Based Accuracy Classification (IBAC) versus Crystal Structure Deviations(2004)125 cited
- → Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery(2010)123 cited