Ioannis Assiotis
Institute of Cancer Research(GB)
Publications by Year
Research Areas
PARP inhibition in cancer therapy, BRCA gene mutations in cancer, Cancer Genomics and Diagnostics, Genetic factors in colorectal cancer, Ovarian cancer diagnosis and treatment
Most-Cited Works
- → Genome-wide Profiling of Genetic Synthetic Lethality Identifies CDK12 as a Novel Determinant of PARP1/2 Inhibitor Sensitivity(2013)363 cited
- → Secondary mutations in BRCA2 associated with clinical resistance to a PARP inhibitor(2012)334 cited
- → Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C(2014)273 cited
- → A Genetic Screen Using the PiggyBac Transposon in Haploid Cells Identifies Parp1 as a Mediator of Olaparib Toxicity(2013)174 cited
- → Frequent germline deleterious mutations in DNA repair genes in familial prostate cancer cases are associated with advanced disease(2014)151 cited
- → Genome-wide functional screen identifies a compendium of genes affecting sensitivity to tamoxifen(2011)147 cited
- → Efficacy of Chemotherapy in BRCA1/2 Mutation Carrier Ovarian Cancer in the Setting of PARP Inhibitor Resistance: A Multi-Institutional Study(2013)140 cited
- → Capture Hi-C identifies putative target genes at 33 breast cancer risk loci(2018)131 cited
- → Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor(2017)128 cited
- → High-throughput RNA interference screening using pooled shRNA libraries and next generation sequencing(2011)123 cited