James Fossetta
Bedford Research Foundation(US)
Publications by Year
Research Areas
Cytokine Signaling Pathways and Interactions, Synthesis and biological activity, Immune Response and Inflammation, Chemokine receptors and signaling, Quinazolinone synthesis and applications
Most-Cited Works
- → Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation.(1999)454 cited
- → Pharmacological Characterization of Sch527123, a Potent Allosteric CXCR1/CXCR2 Antagonist(2007)127 cited
- → Discovery of 2-Hydroxy-N,N-dimethyl-3-{2-[[(R)-1-(5- methylfuran-2-yl)propyl]amino]-3,4-dioxocyclobut-1-enylamino}benzamide (SCH 527123): A Potent, Orally Bioavailable CXCR2/CXCR1 Receptor Antagonist(2006)113 cited
- → The carboxyl-terminal region of human interferon γ is important for biological activity: mutagenic and NMR analysis(1991)67 cited
- → Pharmacological Analysis of Calcium Responses Mediated by the Human A3 Adenosine Receptor in Monocyte-Derived Dendritic Cells and Recombinant Cells(2003)63 cited
- → Facile synthesis of tetracyclic azepine and oxazocine derivatives and their potential as MAPKAP-K2 (MK2) inhibitors(2011)56 cited
- → Potent and Selective Amidopyrazole Inhibitors of IRAK4 That Are Efficacious in a Rodent Model of Inflammation(2015)40 cited
- → Expression of human inducible nitric oxide synthase in Escherichia coli(1996)37 cited
- → Characterization of Peripheral Human Cannabinoid Receptor (hCB2) Expression and Pharmacology Using a Novel Radioligand, [35S]Sch225336(2006)30 cited
- → Discovery and Structure Enabled Synthesis of 2,6-Diaminopyrimidin-4-one IRAK4 Inhibitors(2015)27 cited