Richard Rampulla
Bristol-Myers Squibb (United States)(US)
Publications by Year
Research Areas
Chemical Synthesis and Analysis, Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Synthesis and Biological Evaluation, Synthesis of heterocyclic compounds
Most-Cited Works
- → Thiophene systems. 9. Thienopyrimidinedione derivatives as potential antihypertensive agents(1988)177 cited
- → Discovery of Branebrutinib (BMS-986195): A Strategy for Identifying a Highly Potent and Selective Covalent Inhibitor Providing Rapid in Vivo Inactivation of Bruton’s Tyrosine Kinase (BTK)(2019)106 cited
- → Discovery of Clinical Candidate BMS-906024: A Potent Pan-Notch Inhibitor for the Treatment of Leukemia and Solid Tumors(2015)88 cited
- → Discovery and Preclinical Pharmacology of an Oral Bromodomain and Extra-Terminal (BET) Inhibitor Using Scaffold-Hopping and Structure-Guided Drug Design(2021)42 cited
- → Potent Inhibitors of Hepatitis C Virus NS3 Protease: Employment of a Difluoromethyl Group as a Hydrogen-Bond Donor(2018)40 cited
- → Rationally Designed, Conformationally Constrained Inverse Agonists of RORγt—Identification of a Potent, Selective Series with Biologic-Like in Vivo Efficacy(2019)37 cited
- → Chemical Modification of Linkers Provides Stable Linker–Payloads for the Generation of Antibody–Drug Conjugates(2020)37 cited
- → Discovery of Pyrrolidine-Containing GPR40 Agonists: Stereochemistry Effects a Change in Binding Mode(2017)30 cited
- → Discovery of a Potent Acyclic, Tripeptidic, Acyl Sulfonamide Inhibitor of Hepatitis C Virus NS3 Protease as a Back-up to Asunaprevir with the Potential for Once-Daily Dosing(2016)30 cited
- → Intramolecular [2+2] Cycloaddition of N‐Allylcinnamamines and N‐Allylcinnamamides by Visible‐Light Photocatalysis(2019)26 cited