Kevin R. Criscione
University of Kansas(US)
Publications by Year
Research Areas
Synthesis and Biological Activity, Chemical Synthesis and Analysis, Berberine and alkaloids research, Traditional and Medicinal Uses of Annonaceae, Carbohydrate Chemistry and Synthesis
Most-Cited Works
- → Effect of Ring Size or an Additional Heteroatom on the Potency and Selectivity of Bicyclic Benzylamine-Type Inhibitors of PhenylethanolamineN-Methyltransferase1a(1996)76 cited
- → Application of the Goldilocks Effect to the Design of Potent and Selective Inhibitors of PhenylethanolamineN-Methyltransferase: Balancing pKaand Steric Effects in the Optimization of 3-Methyl-1,2,3,4-tetrahydroisoquinoline Inhibitors by β-Fluorination(2006)51 cited
- → Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors(2010)45 cited
- → Synthesis and Biochemical Evaluation of 3-Fluoromethyl-1,2,3,4-tetrahydroisoquinolines as Selective Inhibitors of Phenylethanolamine N-Methyltransferase versus the α2-Adrenoceptor(1999)44 cited
- → Comparison of the Binding of 3-Fluoromethyl-7-sulfonyl-1,2,3,4-tetrahydroisoquinolines with Their Isosteric Sulfonamides to the Active Site of PhenylethanolamineN-Methyltransferase(2006)40 cited
- → Synthesis and Evaluation of 3-Trifluoromethyl-7-substituted- 1,2,3,4-tetrahydroisoquinolines as Selective Inhibitors of PhenylethanolamineN-Methyltransferase versus the α2-Adrenoceptor(1999)35 cited
- → Inhibitors of phenylethanolamine N-methyltransferase devoid of α2-adrenoceptor affinity(2005)32 cited
- → Molecular recognition of physiological substrate noradrenaline by the adrenaline-synthesizing enzyme PNMT and factors influencing its methyltransferase activity(2009)32 cited
- → Synthesis and Evaluation of 4-Fluoro-8-substituted-2,3,4,5-tetrahydro-1H-2-benzazapines as Selective Inhibitors of Phenylethanolamine N-Methyltransferase versus the α2-Adrenoceptor(2001)28 cited
- → Examination of the Role of the Acidic Hydrogen in Imparting Selectivity of 7-(Aminosulfonyl)-1,2,3,4-tetrahydroisoquinoline (SK&F 29661) Toward Inhibition of Phenylethanolamine N-Methyltransferase vs the α2-Adrenoceptor1a(1997)26 cited