Frédéric Lessard
Université Laval(CA)
Publications by Year
Research Areas
RNA modifications and cancer, RNA Research and Splicing, Cancer-related Molecular Pathways, Advanced Breast Cancer Therapies, RNA and protein synthesis mechanisms
Most-Cited Works
- → Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation(2013)190 cited
- → Senescence-associated ribosome biogenesis defects contributes to cell cycle arrest through the Rb pathway(2018)176 cited
- → New Insights into CDK Regulators: Novel Opportunities for Cancer Therapy(2021)125 cited
- → Loss of Human Ribosomal Gene CpG Methylation Enhances Cryptic RNA Polymerase II Transcription and Disrupts Ribosomal RNA Processing(2009)114 cited
- → The ARF Tumor Suppressor Controls Ribosome Biogenesis by Regulating the RNA Polymerase I Transcription Factor TTF-I(2010)97 cited
- → Conditional Inactivation of Upstream Binding Factor Reveals Its Epigenetic Functions and the Existence of a Somatic Nucleolar Precursor Body(2014)89 cited
- → NFE2L3 Controls Colon Cancer Cell Growth through Regulation of DUX4, a CDK1 Inhibitor(2019)84 cited
- → The chemotherapeutic agent CX-5461 irreversibly blocks RNA polymerase I initiation and promoter release to cause nucleolar disruption, DNA damage and cell inviability(2020)82 cited
- → A CDK4/6-Dependent Epigenetic Mechanism Protects Cancer Cells from PML-induced Senescence(2016)63 cited
- → Cellular senescence and protein degradation(2014)61 cited