Jaclyn L. Henderson
Jnana Therapeutics (United States)(US)
Publications by Year
Research Areas
Catalytic Cross-Coupling Reactions, Catalytic C–H Functionalization Methods, Cyclization and Aryne Chemistry, Alzheimer's disease research and treatments, Chemical synthesis and alkaloids
Most-Cited Works
- → Palladium-catalyzed coupling of functionalized primary and secondary amines with aryl and heteroaryl halides: two ligands suffice in most cases(2010)355 cited
- → Mechanism-Based Inactivation (MBI) of Cytochrome P450 Enzymes: Structure–Activity Relationships and Discovery Strategies To Mitigate Drug–Drug Interaction Risks(2012)216 cited
- → Discovery and Preclinical Profiling of 3-[4-(Morpholin-4-yl)-7 H -pyrrolo[2,3- d ]pyrimidin-5-yl]benzonitrile (PF-06447475), a Highly Potent, Selective, Brain Penetrant, and in Vivo Active LRRK2 Kinase Inhibitor(2014)180 cited
- → The Benzyne Aza‐Claisen Reaction(2009)120 cited
- → Biaryl Synthesis via Palladium-Catalyzed Aryne Multicomponent Coupling(2007)79 cited
- → Efficient Pd-Catalyzed Amination Reactions for Heterocycle Functionalization(2010)67 cited
- → Palladium-Catalyzed Amination of Unprotected Halo-7-azaindoles(2010)61 cited
- → Palladium-Catalyzed N-Arylation of 2-Aminothiazoles(2012)56 cited
- → Design and Optimization of Selective Protein Kinase C θ (PKCθ) Inhibitors for the Treatment of Autoimmune Diseases(2013)47 cited
- → Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo(2021)33 cited