Johannes Voigt
Karlsruhe Institute of Technology(DE)HEM Technologies (United States)(US)Foghorn Therapeutics (United States)(US)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Chemical Synthesis and Analysis, Chromatin Remodeling and Cancer, Protein Tyrosine Phosphatases, Protein Kinase Regulation and GTPase Signaling
Most-Cited Works
- → Comparison of the NCI Open Database with Seven Large Chemical Structural Databases(2001)217 cited
- → Discovery of Novel Chemotypes to a G-Protein-Coupled Receptor through Ligand-Steered Homology Modeling and Structure-Based Virtual Screening(2008)169 cited
- → Discovery of the 3-Imino-1,2,4-thiadiazinane 1,1-Dioxide Derivative Verubecestat (MK-8931)–A β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor for the Treatment of Alzheimer’s Disease(2016)161 cited
- → Structure based design of iminohydantoin BACE1 inhibitors: Identification of an orally available, centrally active BACE1 inhibitor(2012)151 cited
- → Discovery of Cyclic Acylguanidines as Highly Potent and Selective β-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I—Inhibitor Design and Validation(2009)121 cited
- → Enhanced CACTVS Browser of the Open NCI Database(2002)107 cited