Sreekanth Kokkonda
University of Washington(US)
Publications by Year
Research Areas
HIV/AIDS drug development and treatment, Biochemical and Molecular Research, Pneumocystis jirovecii pneumonia detection and treatment, Malaria Research and Control, Cancer therapeutics and mechanisms
Most-Cited Works
- → A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria(2015)369 cited
- → Structure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies PotentPlasmodium falciparumDihydroorotate Dehydrogenase Inhibitors with Clinical Candidate Potential(2011)283 cited
- → Fluorine Modulates Species Selectivity in the Triazolopyrimidine Class of Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors(2014)109 cited
- → A Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Improved Drug-like Properties for Treatment and Prevention of Malaria(2016)86 cited
- → Bioisosteric Transformations and Permutations in the Triazolopyrimidine Scaffold To Identify the Minimum Pharmacophore Required for Inhibitory Activity againstPlasmodium falciparumDihydroorotate Dehydrogenase(2012)69 cited
- → Tetrahydro-2-naphthyl and 2-Indanyl Triazolopyrimidines Targeting Plasmodium falciparum Dihydroorotate Dehydrogenase Display Potent and Selective Antimalarial Activity(2016)58 cited
- → Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series(2021)45 cited
- → Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria(2020)36 cited
- → Isoxazolopyrimidine-Based Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Antimalarial Activity(2018)32 cited
- → Topoisomerase II from Human Malaria Parasites(2015)21 cited