B Ermel
Hospital de Clínicas de Porto Alegre(BR)
Publications by Year
Research Areas
Metabolism, Diabetes, and Cancer, Protein Kinase Regulation and GTPase Signaling, Adipose Tissue and Metabolism, Pancreatic function and diabetes, Cellular transport and secretion
Most-Cited Works
- → Decreased tyrosine kinase activity of insulin receptor isolated from rat adipocytes rendered insulin-resistant by catecholamine treatment in vitro(1986)117 cited
- → A defective Intramolecular Autoactivation Cascade May Cause the Reduced Kinase Activity of the Skeletal Muscle Insulin Receptor from Patients with Non-insulin-dependent Diabetes Mellitus(1989)109 cited
- → The two isotypes of the human insulin receptor (HIR-A and HIR-B) follow different internalization kinetics(1991)104 cited
- → Prevention by Protein Kinase C Inhibitors of Glucose-Induced Insulin-Receptor Tyrosine Kinase Resistance in Rat Fat Cells(1991)98 cited
- → Insulin rapidly stimulates phosphorylation of a 46-kDa membrane protein on tyrosine residues as well as phosphorylation of several soluble proteins in intact fat cells.(1987)97 cited
- → Tumor-promoting phorbol esters increase the Km of the ATP-binding site of the insulin receptor kinase from rat adipocytes.(1986)96 cited
- → Distinct .alpha.-subunit structures of human insulin receptor A and B variants determine differences in tyrosine kinase activities(1992)80 cited
- Mannose, glucosamine and inositol monophosphate inhibit the effects of insulin on lipogenesis. Further evidence for a role for inositol phosphate-oligosaccharides in insulin action.(1990)
- → Further evidence for a two-step model of glucose-transport regulation. Inositol phosphate-oligosaccharides regulate glucose-carrier activity(1989)51 cited
- → An altered IGF-I receptor is present in human leukemic cells.(1990)44 cited