Rajeshri G. Karki
Novartis (Switzerland)(CH)Dhulikhel Hospital(NP)
Publications by Year
Research Areas
Chemical Synthesis and Analysis, HIV/AIDS drug development and treatment, Complement system in diseases, Biochemical and Molecular Research, HIV Research and Treatment
Most-Cited Works
- → Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex(2019)249 cited
- → Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers(2018)228 cited
- → Small-molecule factor B inhibitor for the treatment of complement-mediated diseases(2019)211 cited
- → Metal-Dependent Inhibition of HIV-1 Integrase by β-Diketo Acids and Resistance of the Soluble Double-Mutant (F185K/C280S)(2003)132 cited
- → Medicinal Chemistry Profiling of Monocyclic 1,2‐Azaborines(2017)116 cited
- → Metal-Dependent Inhibition of HIV-1 Integrase(2002)86 cited
- → Structure of neprilysin in complex with the active metabolite of sacubitril(2016)67 cited
- → PDB Ligand Conformational Energies Calculated Quantum-Mechanically(2012)64 cited
- → Azido-Containing aryl β-Diketo acid HIV-1 integrase inhibitors(2003)60 cited
- → Discovery of 4-((2 S ,4 S )-4-Ethoxy-1-((5-methoxy-7-methyl-1 H -indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases(2020)59 cited