Patrick A. Marcotte
Publications by Year
Research Areas
Peptidase Inhibition and Analysis, Protease and Inhibitor Mechanisms, Histone Deacetylase Inhibitors Research, Receptor Mechanisms and Signaling, Protein Degradation and Inhibitors
Most-Cited Works
- → Discovery of Potent Nonpeptide Inhibitors of Stromelysin Using SAR by NMR(1997)317 cited
- → Inactivation of aromatase in vitro by 4-hydroxy-4-androstene-3,17-dione and 4-acetoxy-4-androstene-3,17-dione and sustained effects in vivo(1981)215 cited
- → Discovery ofN-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N‘-(2-fluoro-5-methylphenyl)urea (ABT-869), a 3-Aminoindazole-Based Orally Active Multitargeted Receptor Tyrosine Kinase Inhibitor(2007)184 cited
- → Thienopyrimidine Ureas as Novel and Potent Multitargeted Receptor Tyrosine Kinase Inhibitors(2005)152 cited
- → Trifluoromethyl ketones as inhibitors of histone deacetylase(2002)147 cited
- → Succinimide hydroxamic acids as potent inhibitors of histone deacetylase (HDAC)(2002)113 cited
- → Synthesis and Evaluation of a New Generation of Orally Efficacious Benzimidazole-Based Poly(ADP-ribose) Polymerase-1 (PARP-1) Inhibitors as Anticancer Agents(2009)108 cited
- → Phenoxyphenyl SulfoneN-Formylhydroxylamines (Retrohydroxamates) as Potent, Selective, Orally Bioavailable Matrix Metalloproteinase Inhibitors(2001)103 cited
- → Suicide inactivation of bacterial cystathionine .gamma.-synthase and methionine .gamma.-lyase during processing of L-propargylglycine(1979)89 cited
- → Stromelysin Inhibitors Designed from Weakly Bound Fragments: Effects of Linking and Cooperativity(1997)87 cited