Ayesha Sitlani
California Institute of Technology(US)
Publications by Year
Research Areas
Lipoproteins and Cardiovascular Health, Estrogen and related hormone effects, DNA and Nucleic Acid Chemistry, Metal complexes synthesis and properties, Computational Drug Discovery Methods
Most-Cited Works
- → DNA photocleavage by phenanthrenequinone diimine complexes of rhodium(III): shape-selective recognition and reaction(1992)378 cited
- → Mechanistic implications for LDL receptor degradation from the PCSK9/LDLR structure at neutral pH(2011)233 cited
- → Effects of pH and Low Density Lipoprotein (LDL) on PCSK9-dependent LDL Receptor Regulation(2007)188 cited
- → Structural and Biochemical Characterization of the Wild Type PCSK9-EGF(AB) Complex and Natural Familial Hypercholesterolemia Mutants(2008)136 cited
- → A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo1[S](2010)133 cited
- → A Proprotein Convertase Subtilisin-like/Kexin Type 9 (PCSK9) C-terminal Domain Antibody Antigen-binding Fragment Inhibits PCSK9 Internalization and Restores Low Density Lipoprotein Uptake(2010)107 cited
- → An Anti-PCSK9 Antibody Reduces LDL-Cholesterol On Top Of A Statin And Suppresses Hepatocyte SREBP-Regulated Genes(2012)103 cited
- → PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain(2010)97 cited
- → Biochemical characterization of cholesteryl ester transfer protein inhibitors(2010)96 cited
- → Identification of a potent synthetic FXR agonist with an unexpected mode of binding and activation(2008)90 cited