André Lechel
University Hospital Ulm(DE)
Publications by Year
Research Areas
Telomeres, Telomerase, and Senescence, Pancreatic and Hepatic Oncology Research, Cancer Genomics and Diagnostics, Protein Degradation and Inhibitors, Advanced Breast Cancer Therapies
Most-Cited Works
- → Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation(2006)418 cited
- → A Differentiation Checkpoint Limits Hematopoietic Stem Cell Self-Renewal in Response to DNA Damage(2012)338 cited
- → Loss of p53 in Enterocytes Generates an Inflammatory Microenvironment Enabling Invasion and Lymph Node Metastasis of Carcinogen-Induced Colorectal Tumors(2012)298 cited
- → p53-Dependent Nestin Regulation Links Tumor Suppression to Cellular Plasticity in Liver Cancer(2014)221 cited
- → Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling(2016)209 cited
- → Telomerase gene mutations are associated with cirrhosis formation(2011)172 cited
- → Exonuclease-1 Deletion Impairs DNA Damage Signaling and Prolongs Lifespan of Telomere-Dysfunctional Mice(2007)146 cited
- → Telomeres shorten while Tert expression increases during ageing of the short-lived fish Nothobranchius furzeri(2009)145 cited
- → Telomere shortening and inactivation of cell cycle checkpoints characterize human hepatocarcinogenesis†(2007)144 cited
- → Loss of ATM accelerates pancreatic cancer formation and epithelial–mesenchymal transition(2015)135 cited