Marc O’Reilly
Publications by Year
Research Areas
Melanoma and MAPK Pathways, Synthesis and biological activity, Computational Drug Discovery Methods, Enzyme Structure and Function, Cancer-related Molecular Pathways
Most-Cited Works
- → Serine is a natural ligand and allosteric activator of pyruvate kinase M2(2012)654 cited
- → Identification of N-(4-Piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide (AT7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment-Based X-Ray Crystallography and Structure Based Drug Design(2008)337 cited
- → Fragment-Based Discovery of the Pyrazol-4-yl Urea (AT9283), a Multitargeted Kinase Inhibitor with Potent Aurora Kinase Activity(2008)330 cited
- → Crystal structure of human CDK4 in complex with a D-type cyclin(2009)226 cited
- → Identification of Novel p38α MAP Kinase Inhibitors Using Fragment-Based Lead Generation(2004)185 cited
- → Control by phosphorylation(1996)111 cited
- → Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design(2019)95 cited
- → 4-(Pyrazol-4-yl)-pyrimidines as Selective Inhibitors of Cyclin-Dependent Kinase 4/6(2010)91 cited
- → Pharmacologic Activation of PKM2 Slows Lung Tumor Xenograft Growth(2013)69 cited
- → Fragment-Based Discovery of a Potent, Orally Bioavailable Inhibitor That Modulates the Phosphorylation and Catalytic Activity of ERK1/2(2018)65 cited