Geraldine Harriman
Io Therapeutics (United States)(US)
Publications by Year
Research Areas
Cancer Treatment and Pharmacology, Synthetic Organic Chemistry Methods, Cancer, Lipids, and Metabolism, Cancer, Hypoxia, and Metabolism, Microbial Natural Products and Biosynthesis
Most-Cited Works
- → Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models(2016)506 cited
- → Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma(2018)403 cited
- → Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats(2016)276 cited
- → Acetyl‐coenzyme A carboxylase inhibition reduces de novo lipogenesis in overweight male subjects: A randomized, double‐blind, crossover study(2017)115 cited
- → A Selective Small Molecule IκB Kinase β Inhibitor Blocks Nuclear Factor κB-Mediated Inflammatory Responses in Human Fibroblast-Like Synoviocytes, Chondrocytes, and Mast Cells(2006)112 cited
- → Synthesis of small and medium sized 2,2-disubstituted lactams via the “intramolecular” three component Ugi reaction(1997)80 cited
- → IKKβ inhibition protects against bone and cartilage destruction in a rat model of rheumatoid arthritis(2006)79 cited
- → Accelerating drug discovery through tight integration of expert molecular design and predictive scoring(2016)70 cited
- → A Facile One-Flask Conversion of Aldehydes and Ketones to N-Sulfonyl Imines(1995)65 cited
- → Synthesis, Conformational Analysis, and Biological Evaluation of Heteroaromatic Taxanes(1996)52 cited