Paul Smith
University of Melbourne(AU)Edinburgh Cancer Research(GB)St Vincent's Hospital(AU)
Publications by Year
Research Areas
Ubiquitin and proteasome pathways, Cancer-related Molecular Pathways, Protein Degradation and Inhibitors, Epigenetics and DNA Methylation, Cancer, Hypoxia, and Metabolism
Most-Cited Works
- → DRAM, a p53-Induced Modulator of Autophagy, Is Critical for Apoptosis(2006)1,341 cited
- → p53 mutation with frequent novel codons but not a mutator phenotype in BRCA1- and BRCA2-associated breast tumours(1998)178 cited
- Arylamine N-acetyltransferase-1 is highly expressed in breast cancers and conveys enhanced growth and resistance to etoposide in vitro.(2003)
- → Novel p53 mutants selected in BRCA-associated tumours which dissociate transformation suppression from other wild-type p53 functions(1999)107 cited
- → Epigenetic downregulation of human disabled homolog 2 switches TGF-β from a tumor suppressor to a tumor promoter(2010)101 cited
- → Discovery of an MLLT1/3 YEATS Domain Chemical Probe(2018)91 cited
- → The role of E3 ubiquitin ligases in the development and progression of glioblastoma(2021)83 cited