Francis Y. F. Lee
Publications by Year
Research Areas
Cancer Treatment and Pharmacology, Chronic Lymphocytic Leukemia Research, Chronic Myeloid Leukemia Treatments, Microtubule and mitosis dynamics, Cancer-related Molecular Pathways
Most-Cited Works
- → The Structure of Dasatinib (BMS-354825) Bound to Activated ABL Kinase Domain Elucidates Its Inhibitory Activity against Imatinib-Resistant ABL Mutants(2006)678 cited
- BMS-247550: a novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacy.(2001)
- → Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome–positive leukemia(2008)438 cited
- → N-(Cycloalkylamino)acyl-2-aminothiazole Inhibitors of Cyclin-Dependent Kinase 2. N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4- piperidinecarboxamide (BMS-387032), a Highly Efficacious and Selective Antitumor Agent(2004)251 cited
- → Metabolism and Disposition of Dasatinib after Oral Administration to Humans(2008)194 cited
- → A Novel Application of a Pd(0)-Catalyzed Nucleophilic Substitution Reaction to the Regio- and Stereoselective Synthesis of Lactam Analogues of the Epothilone Natural Products(2000)141 cited
- → Discovery of (R)-7-Cyano-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine (BMS-214662), a Farnesyltransferase Inhibitor with Potent Preclinical Antitumor Activity(2000)134 cited
- → Targeting DDR2 enhances tumor response to anti–PD-1 immunotherapy(2019)125 cited
- → Preclinical discovery of ixabepilone, a highly active antineoplastic agent(2008)119 cited
- Preclinical antitumor activity of BMS-214662, a highly apoptotic and novel farnesyltransferase inhibitor.(2001)