F.F. Vajdos

Publications by Year

Research Areas

Computational Drug Discovery Methods, Cytokine Signaling Pathways and Interactions, HER2/EGFR in Cancer Research, Protein Structure and Dynamics, X-ray Diffraction in Crystallography

Most-Cited Works

• → How to measure and predict the molar absorption coefficient of a protein(1995)3,888 cited
• → Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex(2004)1,103 cited
• → Crystal Structure of Human Cyclophilin A Bound to the Amino-Terminal Domain of HIV-1 Capsid(1996)699 cited
• → Structure of the Carboxyl-Terminal Dimerization Domain of the HIV-1 Capsid Protein(1997)588 cited
• → Antitumor Activity and Pharmacology of a Selective Focal Adhesion Kinase Inhibitor, PF-562,271(2008)380 cited
• → Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition(2016)191 cited
• → Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( S )-2,2-Difluorocyclopropyl)((1 R ,5 S )-3-(2-((1-methyl-1 H -pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841)(2018)170 cited
• → Design of a Janus Kinase 3 (JAK3) Specific Inhibitor 1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one (PF-06651600) Allowing for the Interrogation of JAK3 Signaling in Humans(2017)160 cited
• → Structural insights into the catalytic mechanism of cyclophilin A(2003)148 cited
• → Suppressor of Fused Regulates Gli Activity through a Dual Binding Mechanism(2004)123 cited