David E. Root
Broad Institute(US)
Publications by Year
Research Areas
CRISPR and Genetic Engineering, Protein Degradation and Inhibitors, Cancer Genomics and Diagnostics, RNA modifications and cancer, Radio Frequency Integrated Circuit Design
Most-Cited Works
- → Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells(2013)5,440 cited
- → Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9(2016)4,854 cited
- → Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1(2009)4,112 cited
- → A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles(2017)3,590 cited
- → Defining a Cancer Dependency Map(2017)3,360 cited
- → Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells(2017)2,117 cited
- → lincRNAs act in the circuitry controlling pluripotency and differentiation(2011)