Lubomir V. Nechev
Alnylam Pharmaceuticals (United States)(US)
Publications by Year
Research Areas
DNA and Nucleic Acid Chemistry, DNA Repair Mechanisms, Carcinogens and Genotoxicity Assessment, RNA Interference and Gene Delivery, Advanced biosensing and bioanalysis techniques
Most-Cited Works
- → Rational design of cationic lipids for siRNA delivery(2010)1,750 cited
- → RNAi-mediated gene silencing in non-human primates(2006)1,342 cited
- → A combinatorial library of lipid-like materials for delivery of RNAi therapeutics(2008)1,215 cited
- → Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates(2008)636 cited
- → Evaluation of the safety, tolerability and pharmacokinetics of ALN-RSV01, a novel RNAi antiviral therapeutic directed against respiratory syncytial virus (RSV)(2008)245 cited
- → DNA Interchain Cross-Links Formed by Acrolein and Crotonaldehyde(2002)191 cited
- → Unique Gene‐Silencing and Structural Properties of 2′‐Fluoro‐Modified siRNAs(2011)184 cited
- → RNA Interference-Mediated Silencing of the Respiratory Syncytial Virus Nucleocapsid Defines a Potent Antiviral Strategy(2009)144 cited
- → DNA Interstrand Cross-Links Induce Futile Repair Synthesis in Mammalian Cell Extracts(2000)117 cited
- → Evaluation of the Mutagenic Potential of the Principal DNA Adduct of Acrolein(2001)109 cited