Frans Janssens
Janssen (Belgium)(BE)
Publications by Year
Research Areas
Neuropeptides and Animal Physiology, Receptor Mechanisms and Signaling, Respiratory viral infections research, Synthesis of heterocyclic compounds, Phenothiazines and Benzothiazines Synthesis and Activities
Most-Cited Works
- → Substituted benzimidazoles with nanomolar activity against respiratory syncytial virus(2003)115 cited
- → Selection of a Respiratory Syncytial Virus Fusion Inhibitor Clinical Candidate. 2. Discovery of a Morpholinopropylaminobenzimidazole Derivative (TMC353121)(2008)98 cited
- → New antihistaminic N-heterocyclic 4-piperidinamines. 1. Synthesis and antihistaminic activity of N-(4-piperidinyl)-1H-benzimidazol-2-amines(1985)91 cited
- → Synthetic 1,4-disubstituted 1,4-dihydro-5H-tetrazol-5-one derivatives of fentanyl: Alfentanil (R 39209), a potent, extremely short-acting narcotic analgesic(1986)56 cited
- → Stereochemistry and mechanism of acylation of acetylenes(1975)52 cited
- → Selection of a Respiratory Syncytial Virus Fusion Inhibitor Clinical Candidate, Part 1: Improving the Pharmacokinetic Profile Using the Structure−Property Relationship(2007)51 cited
- In vivo pharmacology of astemizole, a new type of H1-antihistaminic compound.(1981)
- → New antihistaminic N-heterocyclic 4-piperidinamines. 3. Synthesis and antihistaminic activity of N-(4-piperidinyl)-3H-imidazo[4,5-b]pyridin-2-amines(1985)47 cited
- → New antihistaminic N-heterocyclic 4-piperidinamines. 2. Synthesis and antihistaminic activity of 1-[(4-fluorophenyl)methyl]-N-(4-piperidinyl)-1H-benzimidazol-2-amines(1985)46 cited
- → Pharmacological Profile of (2 R-trans)-4-[1-[3,5-bis(Trifluoromethyl)benzoyl]-2-(phenylmethyl)-4-piperidinyl]-N-(2,6-dimethylphenyl)-1-acetamide (S)-Hydroxybutanedioate (R116301), an Orally and Centrally Active Neurokinin-1 Receptor Antagonist(2002)26 cited