Jamie Shields

Publications by Year

Research Areas

Ubiquitin and proteasome pathways, Protein Degradation and Inhibitors, Multiple Myeloma Research and Treatments, Histone Deacetylase Inhibitors Research, Parkinson's Disease Mechanisms and Treatments

Most-Cited Works

• → A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis(2009)590 cited
• → Design and Synthesis of an Orally Bioavailable and Selective Peptide Epoxyketone Proteasome Inhibitor (PR-047)(2009)271 cited
• → Preclinical Pharmacology and in Vitro Characterization of PR-047, An Oral Inhibitor of the 20S Proteasome(2008)5 cited
• → Some Derivatives of Phenethanolamine as MAO Inhibitors(1970)3 cited
• → Erratum: A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis(2009)1 cited
• The selective proteasome inhibitor carfilzomib synergizes with the histone deacetylase (HDAC) inhibitor vorinostat in preclinical models of non-Hodgkin’s lymphoma and solid tumors(2008)
• Development of peptide epoxyketone-based proteasome inhibitors(2007)
• → ChemInform Abstract: EINIGE DERIVATE DES PHENAETHANOLAMINS ALS MONOAMINOOXIDASE‐INHIBITOREN(1970)