Ernest Hamel
National Institutes of Health(US)Government of the United States of America(US)Frederick National Laboratory for Cancer Research(US)National Cancer Institute(US)
Publications by Year
Research Areas
Synthesis and biological activity, Click Chemistry and Applications, Cancer Treatment and Pharmacology, Synthesis and Biological Evaluation, Microtubule and mitosis dynamics
Most-Cited Works
- → Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4(1989)785 cited
- → Activities of the Microtubule-stabilizing Agents Epothilones A and B with Purified Tubulin and in Cells Resistant to Paclitaxel (Taxol®)(1997)512 cited
- → Antimitotic natural products combretastatin A-4 and combretastatin A-2: studies on the mechanism of their inhibition of the binding of colchicine to tubulin(1989)414 cited
- → 2-Methoxyestradiol, an endogenous mammalian metabolite, inhibits tubulin polymerization by interacting at the colchicine site.(1994)408 cited
- → 6-Alkylamino- and 2,3-Dihydro-3‘-methoxy-2-phenyl-4-quinazolinones and Related Compounds: Their Synthesis, Cytotoxicity, and Inhibition of Tubulin Polymerization(2000)407 cited
- → Synthesis of epothilones A and B in solid and solution phase(1997)398 cited