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Siraj M. Ali | doi.page

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Siraj M. Ali

UPMC Hillman Cancer Center(US)University of Pittsburgh Medical Center(US)

Publications by Year

Research Areas

Cancer Genomics and Diagnostics, Lung Cancer Treatments and Mutations, Genetic factors in colorectal cancer, Colorectal Cancer Treatments and Studies, Bladder and Urothelial Cancer Treatments

Most-Cited Works

→ Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex(2005)6,146 cited
→ Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden(2017)3,672 cited
→ mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery(2002)2,961 cited
→ Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton(2004)2,646 cited
→ Prolonged Rapamycin Treatment Inhibits mTORC2 Assembly and Akt/PKB(2006)2,633 cited
→ STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma(2018)1,562 cited

→ Growing roles for the mTOR pathway(2005)

1,547 cited

→ GβL, a Positive Regulator of the Rapamycin-Sensitive Pathway Required for the Nutrient-Sensitive Interaction between Raptor and mTOR(2003)948 cited

→ Activation of MET via Diverse Exon 14 Splicing Alterations Occurs in Multiple Tumor Types and Confers Clinical Sensitivity to MET Inhibitors(2015)791 cited

→ Pembrolizumab as Neoadjuvant Therapy Before Radical Cystectomy in Patients With Muscle-Invasive Urothelial Bladder Carcinoma (PURE-01): An Open-Label, Single-Arm, Phase II Study(2018)721 cited