Sumeet Rana
Array BioPharma (United States)(US)
Publications by Year
Research Areas
Melanoma and MAPK Pathways, Protein Kinase Regulation and GTPase Signaling, Alzheimer's disease research and treatments, Microtubule and mitosis dynamics, Drug Transport and Resistance Mechanisms
Most-Cited Works
- → Inflammatory Biomarkers of Sulfur Mustard Analog 2-Chloroethyl Ethyl Sulfide–Induced Skin Injury in SKH-1 Hairless Mice(2008)82 cited
- → Pyrazolopyridine Inhibitors of B-RafV600E. Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors(2011)66 cited
- → Spirocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors: From Hit to Lowering of Cerebrospinal Fluid (CSF) Amyloid β in a Higher Species(2013)58 cited
- ARRY-520, a novel KSP inhibitor with potent activity in hematological and taxane-resistant tumor models.(2009)
- → Discovery of 7-Tetrahydropyran-2-yl Chromans: β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors That Reduce Amyloid β-Protein (Aβ) in the Central Nervous System(2014)38 cited
- → Abstract 2515: Preclinical Development of ARRY-162, A Potent and Selective MEK 1/2 Inhibitor(2010)37 cited
- → Discovery of a Novel Class of Imidazo[1,2-a]Pyridines with Potent PDGFR Activity and Oral Bioavailability(2013)28 cited
- → Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-RafV600E kinase(2014)19 cited
- → 8-Tetrahydropyran-2-yl Chromans: Highly Selective Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors(2014)18 cited
- → The discovery of potent and selective pyridopyrimidin-7-one based inhibitors of B-RafV600E kinase(2012)17 cited