Paul Rowland
GlaxoSmithKline (Poland)(PL)
Publications by Year
Research Areas
Biochemical and Molecular Research, Computational Drug Discovery Methods, Enzyme Structure and Function, Tryptophan and brain disorders, PI3K/AKT/mTOR signaling in cancer
Most-Cited Works
- → A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response(2012)940 cited
- → Crystal Structure of Human Cytochrome P450 2D6(2005)433 cited
- → Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition(2019)166 cited
- → Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis(2016)157 cited
- → The three–dimensional structure of glucose 6–phosphate dehydrogenase from Leuconostoc mesenteroides refined at 2.0 Å resolution(1994)132 cited
- → Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase δ for the Treatment of Respiratory Disease(2015)131 cited
- → Active Site of Dihydroorotate Dehydrogenase A from Lactococcus lactis Investigated by Chemical Modification and Mutagenesis(1997)102 cited
- → The crystal structure of the flavin containing enzyme dihydroorotate dehydrogenase A from Lactococcus lactis(1997)99 cited
- → N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3(2006)90 cited
- → Glucose 6-phosphate dehydrogenase mutations causing enzyme deficiency in a model of the tertiary structure of the human enzyme(1996)83 cited