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Roger Wrigglesworth | doi.page

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Roger Wrigglesworth

Pfizer (France)(FR)

Publications by Year

Research Areas

Synthesis and Characterization of Heterocyclic Compounds, Synthesis and Biological Evaluation, Quinazolinone synthesis and applications, Chemical Synthesis and Analysis, Biochemical and Molecular Research

Most-Cited Works

→ A new reagent which may be used to introduce sulfhydryl groups into proteins, and its use in the preparation of conjugates for immunoassay(1983)263 cited
→ The Discovery of Capsazepine, the First Competitive Antagonist of the Sensory Neuron Excitants Capsaicin and Resiniferatoxin(1994)209 cited
→ Analogs of capsaicin with agonist activity as novel analgesic agents; structure-activity studies. 1. The aromatic "A-region"(1993)162 cited
→ Analogs of capsaicin with agonist activity as novel analgesic agents; structure-activity studies. 3. The hydrophobic side-chain "C-region"(1993)110 cited
→ Bradyzide, a potent non‐peptide B₂ bradykinin receptor antagonist with long‐lasting oral activity in animal models of inflammatory hyperalgesia(2000)104 cited
→ Similarities and Differences in the Structure−Activity Relationships of Capsaicin and Resiniferatoxin Analogues(1996)93 cited

→ Novel series of 8H-quinazolino[4,3-b]quinazolin-8-ones via two Niementowski condensations(2003)

92 cited

→ Analogs of capsaicin with agonist activity as novel analgesic agents; structure-activity studies. 2. The amide bond "B-region"(1993)83 cited

→ Stereoselective construction of quaternary centers at ambient temperature by the highly stereocontrolled migration of groups containing sp-, sp2-, and sp3-hybridized carbon atoms(1993)78 cited

→ Analogues of Capsaicin with Agonist Activity as Novel Analgesic Agents: Structure−Activity Studies. 4. Potent, Orally Active Analgesics(1996)63 cited